Chromosome 1

1
100,000
200,000
300,000
- 361604 - 359490 Frame -1 non-hemolytic phospholipase C
  matches 97% of B.thailandensis plcN2 non-hemolytic phospholipase C
400,000
500,000
600,000
700,000
800,000
900,000
- RecA B cepacia gene matches 98% to Bps gene Frame +2, Start:903365 End:904405 - found by Yeo Wee Kiang
- MexX-like gene: Frame +1 Start:942895 End:944064 Looks like due to its proximity to the MexY-like gene, which starts a 100 residues downstream, that it is a MexXY-like operon. (See also TBlastn search of NR database showing many related genes. Possibly a superfamily of membrane associated pumps, some of which may be drug efflux pumps.
- MexY-like gene: Frame +1 Start:944167 End:947262 (See MexXY locus below at Chromosome 1 Frame -3 positions 2147000 to 2151000)
1000,000
1100,000
1200,000
1300,000
1400,000
1500,000
1600,000
1700,000
1800,000
1900,000
2000,000
2100,000
- AmrB gene: Frame -3:Start:2150949End:2147821
- MexY gene: Frame -3: Start:2150949 End:2147845 with very good match with P.aeruginosa, 1036 out of 1046 being aligned, and of the aligned residues, 78% are conserved. Note also that this gene is contiguous with the MexX gene starting at 2150949, immediately following the upstream MexX gene (frame -3, ie opposite direction so the numbering is from greater to smaller) which ends at near 2150978, suggesting they belong to the same operon.
- MexX gene: Frame -2: Start:2152138 End:2150978 two gaps and 67% positives over nearly entire length of protein with P.aeruginosa MexX, a new multidrug efflux pump verified by cloning and expression in E.coli.This MexXY system confers higher resistance to fluoroquinolones than the MexAB and MexCD systems, and E. coli ToIC or P. aeruginosa OprM is necessary for the function of the MexXY system (Mine et al, 1999).
  See MexXY-Like genes above at the 942000 to the 944000 positions
2200,000
2300,000
2400,000
2500,000
2600,000
2600,000
2700,000
2800,000
2900,000
3000,000
3100,000
- 3133135 - 3131891 Frame -2 B.pseudomallei maltose-binding protein (malE) gene 1 mismatch 99%
3200,000
3300,000
- 3342761 - 3342171 Frame -1 putative phosphoheptose isomerase GmhA 98% identity to Burkholderia mallei gene. ttw 30 Aug 2002
3400,000
- 3424936 to 3424451 (Frame -2) non-specific DNA binding protein DspA sequence (Genbank entry AY040244.3 GI:22711992)
- ? - 3427??? Frame -? B.pseudomallei catalase-peroxidase protein KatG
- 3429039 - 3428083 Frame -3 oxidative stress regulatory protein OxyR from B.pseudomallei
  100% identity
- 343???? - ? Frame -? B.pseudomallei ATP-dependent DNA helicase protein RecG (recG) gene
- 3442785 - 3444443 Frame +3 Paraquat inducible protein from B.pseudomallei 1 mismatch
3500,000
3600,000
3700,000
3800,000
3900,000
- 3937675 - 3938838 Frame +1 Flagellin gene fliC - Matches 100% to known B.pseudomallei fliC. ttw 2 Sep 2002
4000,000
40+

Chromosome 2

1
100,000
200,000
300,000
400,000
500,000
600,000
700,000
800,000
900,000
1000,000
1100,000
- 1178131-1177523 Frame -1 Burkholderia pseudomallei acyl homoserine lactone synthase (bpsI)
  99% match with B.mallei LuxI quorum-sensing acyl homoserine lactone synthase
  - ttw 2 Sep 2002
1200,000
- 1248195 - 1249079 Frame +3 B.mallei penA Class A beta-lactamase 100% match with B pseudomallei cognate
- 1248195 - 1249079 Frame +3 B.pseudomallei beta-lactamase precursor 2 (blaA-BPS-2) gene
  99% match 2mismatch
- 1248195 - 1249079 Frame +3 B.pseudomallei beta-lactamase precursor 2 (blaA-BPS-1) gene
  99% match 1mismatch
1300,000
1400,000
1500,000
1600,000
1700,000
1800,000
1900,000
2000,000
2100,000
2200,000
2300,000
2400,000
2500,000
2600,000
2600,000
2700,000
- 2702273 - 2701467 Frame -3 Class D beta-lactamase genes from B.pseudomallei
  99% match protein seq E15=1902a ttw 2 Sep 2002
2800,000
2900,000
3000,000

3100,000

AF287634 
Burkholderia pseudomallei insertion sequence ISBp1 transposase A and transposase
B genes, complete cds
gi|14318441|gb|AF287634.3|[14318441]
Both Not found.